VR09 cell line: an EBV-positive lymphoblastoid cell line with in vivo characteristics of diffuse large B cell lymphoma of activated B-cell type.

BACKGROUND: small B-cell neoplasms can show plasmacytic differentiation and may potentially progress to aggressive lymphoma (DLBCL). Epstein-Barr virus (EBV) infection may cause the transformation of malignant cells in vitro. DESIGN AND METHOD: we established VR09 cell line with plasmacytic differen...

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Bibliographic Details
Main Authors: Ilaria Nichele, Alberto Zamò, Anna Bertolaso, Francesco Bifari, Martina Tinelli, Marta Franchini, Roberta Stradoni, Fiorenza Aprili, Giovanni Pizzolo, Mauro Krampera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3528718?pdf=render