A fungal substrate mimicking molecule suppresses plant immunity via an inter-kingdom conserved motif

Pit2 is a secreted Ustilago maydis effector that contributes to corn smut disease by inhibiting papain-like cysteine proteases (PLCPs) in maize. Here Misas Villamil et al. show that Pit2 mimics PLCP substrates, and is cleaved to release a peptide that blocks PLCP activity and represses host immunity...

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Bibliographic Details
Main Authors: Johana C. Misas Villamil, André N. Mueller, Fatih Demir, Ute Meyer, Bilal Ökmen, Jan Schulze Hüynck, Marlen Breuer, Helen Dauben, Joe Win, Pitter F. Huesgen, Gunther Doehlemann
Format: Article
Language:English
Published: Nature Publishing Group 2019-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09472-8