The Recombinant Human Erythropoietin Administered in Neonatal Rats After Excitotoxic Damage Induces Molecular Changes in the Hippocampus

The Recombinant Human Erythropoietin Administered in Neonatal Rats After Excitotoxic Damage Induces Molecular Changes in the Hippocampus

In vitro and in vivo experimental evidence has contributed important knowledge regarding the antiapoptotic effect mediated by EPO signaling in the damaged brain, particularly through different models with a hypoxic component. However, little emphasis has been placed on the effectiveness of rhEPO adm...

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Bibliographic Details
Main Authors: Martha Catalina Rivera-Cervantes, José Jaime Jarero-Basulto, Justo Murguía-Castillo, Alejandra Guadalupe Marín-López, Yadira Gasca-Martínez, Sergio Cornelio-Martínez, Carlos Beas-Zárate
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Neuroscience
Subjects:
monosodium glutamate
erythropoietin
erythropoietin receptor
beta common receptor
recombinant human EPO
excitotoxicity
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00118/full

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https://www.frontiersin.org/article/10.3389/fnins.2019.00118/full

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