Using BAC transgenesis in zebrafish to identify regulatory sequences of the amyloid precursor protein gene in humans
<p>Abstract</p> <p>Background</p> <p>Non-coding DNA in and around the human Amyloid Precursor Protein (APP) gene that is central to Alzheimer’s disease (AD) shares little sequence similarity with that of <it>appb</it> in zebrafish. Identifying DNA domains re...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-09-01
|
| Series: | BMC Genomics |
| Online Access: | http://www.biomedcentral.com/1471-2164/13/451 |