The dynamic shuttling of SIRT1 between cytoplasm and nuclei in bronchial epithelial cells by single and repeated cigarette smoke exposure.

The dynamic shuttling of SIRT1 between cytoplasm and nuclei in bronchial epithelial cells by single and repeated cigarette smoke exposure.

SIRT1 (silent information regulator 2 homolog 1) is a crucial cellular survival protein especially in oxidative stress environments, and has been thought to locate within the nuclei, but also known to shuttle between cytoplasm and nuclei in some cell types. Here, we show for the first time the dynam...

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Bibliographic Details
Main Authors: Satoru Yanagisawa, Jonathan R Baker, Chaitanya Vuppusetty, Takeshi Koga, Thomas Colley, Peter Fenwick, Louise E Donnelly, Peter J Barnes, Kazuhiro Ito
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5839577?pdf=render

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http://europepmc.org/articles/PMC5839577?pdf=render

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