Tenofovir Nephrotoxicity: 2011 Update

Tenofovir is an acyclic nucleotide analogue reverse-transcriptase inhibitor structurally similar to the nephrotoxic drugs adefovir and cidofovir. Tenofovir is widely used to treat HIV infection and approved for treatment of hepatitis B virus. Despite initial cell culture and clinical trials results...

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Bibliographic Details
Main Authors: Beatriz Fernandez-Fernandez, Ana Montoya-Ferrer, Ana B. Sanz, Maria D. Sanchez-Niño, Maria C. Izquierdo, Jonay Poveda, Valeria Sainz-Prestel, Natalia Ortiz-Martin, Alejandro Parra-Rodriguez, Rafael Selgas, Marta Ruiz-Ortega, Jesus Egido, Alberto Ortiz
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:AIDS Research and Treatment
Online Access:http://dx.doi.org/10.1155/2011/354908