A rapid diagnostic workflow for cefotaxime-resistant Escherichia coli and Klebsiella pneumoniae detection from blood cultures by MALDI-TOF mass spectrometry.

A rapid diagnostic workflow for cefotaxime-resistant Escherichia coli and Klebsiella pneumoniae detection from blood cultures by MALDI-TOF mass spectrometry.

Nowadays, the global spread of resistance to oxyimino-cephalosporins in Enterobacteriaceae implies the need for novel diagnostics that can rapidly target resistant organisms from these bacterial species.In this study, we developed and evaluated a Direct Mass Spectrometry assay for Beta-Lactamase (D-...

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Bibliographic Details
Main Authors: Elena De Carolis, Silvia Paoletti, Domenico Nagel, Antonietta Vella, Enrica Mello, Ivana Palucci, Giulia De Angelis, Tiziana D'Inzeo, Maurizio Sanguinetti, Brunella Posteraro, Teresa Spanu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5628900?pdf=render

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http://europepmc.org/articles/PMC5628900?pdf=render

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