ACC2 is expressed at high levels in human white adipose and has an isoform with a novel N-terminus [corrected].

ACC2 is expressed at high levels in human white adipose and has an isoform with a novel N-terminus [corrected].

Acetyl-CoA carboxylases ACC1 and ACC2 catalyze the carboxylation of acetyl-CoA to malonyl-CoA, regulating fatty-acid synthesis and oxidation, and are potential targets for treatment of metabolic syndrome. Expression of ACC1 in rodent lipogenic tissues and ACC2 in rodent oxidative tissues, coupled wi...

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Bibliographic Details
Main Authors: John C Castle, Yoshikazu Hara, Christopher K Raymond, Philip Garrett-Engele, Kenji Ohwaki, Zhengyan Kan, Jun Kusunoki, Jason M Johnson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19190759/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19190759/?tool=EBI

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