METTL3-mediated m6A mRNA modification of FBXW7 suppresses lung adenocarcinoma

METTL3-mediated m6A mRNA modification of FBXW7 suppresses lung adenocarcinoma

Abstract Background FBXW7 m6A modification plays an important role in lung adenocarcinoma (LUAD) progression; however, the underlying mechanisms remain unclear. Methods The correlation between FBXW7 and various genes related to m6A modification was analyzed using The Cancer Genome Atlas database. Th...

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Bibliographic Details
Main Authors: Yingtong Wu, Ning Chang, Yong Zhang, Xinxin Zhang, Leidi Xu, Yinggang Che, Tianyun Qiao, Bin Wu, Ying Zhou, Jun Jiang, Jie Xiong, Jian Zhang
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
METTL3
FBXW7
Lung adenocarcinoma
m6A
Epigenetic modification
Online Access:https://doi.org/10.1186/s13046-021-01880-3

Internet

https://doi.org/10.1186/s13046-021-01880-3

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