Tumoral Environment Triggers Transcript Anomalies in Established Tumors: Induction of Altered Gene Expression and of Aberrant, Truncated and B2 Repeat-Containing Gene Transcripts

Tumoral Environment Triggers Transcript Anomalies in Established Tumors: Induction of Altered Gene Expression and of Aberrant, Truncated and B2 Repeat-Containing Gene Transcripts

In addition to eugenetic changes, cancerous cells exhibit extensive modifications in the expression levels of a variety of genes. The phenotypic switch observed after inoculation of T lymphoma cells into syngenic mice illustrates the active participation of tumoral environment in the induction of a...

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Bibliographic Details
Main Authors: Pieter Rottiers, Marjory Desmedt, Hans Dooms, Roland Contreras, Johan Grooten
Format: Article
Language:English
Published: Elsevier 1999-12-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
mouse cancer
differential gene expression
microenvironment
SINE
subtraction suppression hybridization
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558699800098

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http://www.sciencedirect.com/science/article/pii/S1476558699800098

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