Dissection of the anti-Candida albicans mannan immune response using synthetic oligomannosides reveals unique properties of β-1,2 mannotriose protective epitopes

Dissection of the anti-Candida albicans mannan immune response using synthetic oligomannosides reveals unique properties of β-1,2 mannotriose protective epitopes

Abstract Candida albicans mannan consists of a large repertoire of oligomannosides with different types of mannose linkages and chain lengths, which act as individual epitopes with more or less overlapping antibody specificities. Although anti-C. albicans mannan antibody levels are monitored for dia...

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Bibliographic Details
Main Authors: Boualem Sendid, Karine Lecointe, Mayeul Collot, Pierre-Marie Danzé, Sébastien Damiens, Anne-Sophie Drucbert, Chantal Fradin, Jean-Pierre Vilcot, Frédéric Grenouillet, Faustine Dubar, Jérôme de Ruyck, Samir Jawhara, Jean-Maurice Mallet, Daniel Poulain
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-90402-4

Internet

https://doi.org/10.1038/s41598-021-90402-4

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