Loss of ERα induces amoeboid-like migration of breast cancer cells by downregulating vinculin

Loss of ERα induces amoeboid-like migration of breast cancer cells by downregulating vinculin

Estrogen receptor alpha (ERα)-negative cells, which are enriched during endocrine therapy, are associated with metastatic relapse of breast cancer. Here the authors show that ERα inhibits breast cancer metastasis and suggest that ERα suppresses the amoeboid-like migration of breast cancer cells by u...

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Bibliographic Details
Main Authors: Yuan Gao, Zhaowei Wang, Qiang Hao, Weina Li, Yujin Xu, Juliang Zhang, Wangqian Zhang, Shuning Wang, Shuo Liu, Meng Li, Xiaochang Xue, Wei Zhang, Cun Zhang, Yingqi Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14483

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https://doi.org/10.1038/ncomms14483

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