Oral immunization of a non-recombinant Lactococcus lactis surface displaying influenza hemagglutinin 1 (HA1) induces mucosal immunity in mice.

Mucosal immunization of influenza vaccine is potentially an effective approach for the prevention and control of influenza. The objective of the present study was to evaluate the ability of oral immunization with a non-recombinant Lactococcus lactis displaying HA1/L/AcmA recombinant protein, LL-HA1/...

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Bibliographic Details
Main Authors: Pui-Fong Jee, Vunjia Tiong, Meng-Hooi Shu, Jing-Jing Khoo, Won Fen Wong, Raha Abdul Rahim, Sazaly AbuBakar, Li-Yen Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5673223?pdf=render