Mapping the Interactive Effects of ApoE Gene Polymorphism on Caudate Functional Connectivity in Mild Cognitive Impairment Associated With Parkinson’s Disease

Mapping the Interactive Effects of ApoE Gene Polymorphism on Caudate Functional Connectivity in Mild Cognitive Impairment Associated With Parkinson’s Disease

IntroductionCognitive impairment (CI) is a frequent non-motor symptom of Parkinson’s disease (PD). Caudate and Apolipoprotein E (ApoE) are biomarkers linked to CI in PD. There is little known about whether ApoE affects caudate in mild CI of PD (PD-MCI). We investigated the possible interactive effec...

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Bibliographic Details
Main Authors: Song’an Shang, Yu-Chen Chen, Hongying Zhang, Weiqiang Dou, Long Qian, Xindao Yin, Jingtao Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Neuroscience
Subjects:
Parkinson’s disease
cognitive deficits
magnetic resonance imaging
genetic polymorphism
APOE
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00857/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2020.00857/full

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