Farnesoid X Receptor as Target for Therapies to Treat Cholestasis-Induced Liver Injury

Recent studies on liver disease burden worldwide estimated that cirrhosis is the 11th most common cause of death globally, and there is a great need for new therapies to limit the progression of liver injuries in the early stages. Cholestasis is caused by accumulation of hydrophobic bile acids (BA)...

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Bibliographic Details
Main Authors: Anca D. Petrescu, Sharon DeMorrow
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
FXR
Online Access:https://www.mdpi.com/2073-4409/10/8/1846