Inhibition of NADPH Oxidase Activation by Apocynin Rescues Seizure-Induced Reduction of Adult Hippocampal Neurogenesis

Inhibition of NADPH Oxidase Activation by Apocynin Rescues Seizure-Induced Reduction of Adult Hippocampal Neurogenesis

Apocynin, also known as acetovanillone, is a natural organic compound structurally related to vanillin. Apocynin is known to be an inhibitor of NADPH (Nicotinamide adenine dinucleotide phosphate) oxidase activity and is highly effective in suppressing the production of superoxide. The neuroprotectiv...

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Bibliographic Details
Main Authors: Song Hee Lee, Bo Young Choi, A Ra Kho, Jeong Hyun Jeong, Dae Ki Hong, Dong Hyeon Kang, Beom Seok Kang, Hong Ki Song, Hui Chul Choi, Sang Won Suh
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
epilepsy
pilocarpine
neuron death
NADPH-oxidase inhibitor
oxidative stress
neurogenesis
Online Access:http://www.mdpi.com/1422-0067/19/10/3087

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http://www.mdpi.com/1422-0067/19/10/3087

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