Profiling of the muscle-specific dystroglycan interactome reveals the role of Hippo signaling in muscular dystrophy and age-dependent muscle atrophy

Profiling of the muscle-specific dystroglycan interactome reveals the role of Hippo signaling in muscular dystrophy and age-dependent muscle atrophy

Abstract Background Dystroglycanopathies are a group of inherited disorders characterized by vast clinical and genetic heterogeneity and caused by abnormal functioning of the ECM receptor dystroglycan (Dg). Remarkably, among many cases of diagnosed dystroglycanopathies, only a small fraction can be...

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Bibliographic Details
Main Authors: Andriy S. Yatsenko, Mariya M. Kucherenko, Yuanbin Xie, Dina Aweida, Henning Urlaub, Renate J. Scheibe, Shenhav Cohen, Halyna R. Shcherbata
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Medicine
Subjects:
Dystroglycan
Hippo kinase signaling
Kibra
Yorkie
Proteomics
Muscle degeneration
Online Access:https://doi.org/10.1186/s12916-019-1478-3

Internet

https://doi.org/10.1186/s12916-019-1478-3

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