Quercetin targets cysteine string protein (CSPalpha) and impairs synaptic transmission.

Cysteine string protein (CSPalpha) is a synaptic vesicle protein that displays unique anti-neurodegenerative properties. CSPalpha is a member of the conserved J protein family, also called the Hsp40 (heat shock protein of 40 kDa) protein family, whose importance in protein folding has been recognize...

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Bibliographic Details
Main Authors: Fenglian Xu, Juliane Proft, Sarah Gibbs, Bob Winkfein, Jadah N Johnson, Naweed Syed, Janice E A Braun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2883571?pdf=render