Competition of nuclear factor-erythroid 2 factors related transcription factor isoforms, Nrf1 and Nrf2, in antioxidant enzyme induction

Competition of nuclear factor-erythroid 2 factors related transcription factor isoforms, Nrf1 and Nrf2, in antioxidant enzyme induction

Although the Nrf2 (nuclear factor-erythroid 2 p45 subunit-related factor 2) regulated expression of multiple antioxidant and cytoprotective genes through the electrophile responsive element (EpRE) is well established, interaction of Nrf2/EpRE with Nrf1, a closely-related transcription factor, is le...

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Bibliographic Details
Main Authors: Nikolai L. Chepelev, Hongqiao Zhang, Honglei Liu, Skye McBride, Andrew J. Seal, Todd E. Morgan, Caleb E. Finch, William G. Willmore, Kelvin J.A. Davies, Henry Jay Forman
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Redox Biology
Subjects:
Nrf1
Nrf2
Glutamate cysteine ligase
Electrophile response element
Air pollution
Phase II genes
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231713000268

Internet

http://www.sciencedirect.com/science/article/pii/S2213231713000268

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