Postsynaptic GABABRs Inhibit L-Type Calcium Channels and Abolish Long-Term Potentiation in Hippocampal Somatostatin Interneurons

Postsynaptic GABABRs Inhibit L-Type Calcium Channels and Abolish Long-Term Potentiation in Hippocampal Somatostatin Interneurons

Summary: Inhibition provided by local GABAergic interneurons (INs) activates ionotropic GABAA and metabotropic GABAB receptors (GABABRs). Despite GABABRs representing a major source of inhibition, little is known of their function in distinct IN subtypes. Here, we show that, while the archetypal den...

Full description

Bibliographic Details
Main Authors: Sam A. Booker, Desiree Loreth, Annabelle L. Gee, Masahiko Watanabe, Peter C. Kind, David J.A. Wyllie, Ákos Kulik, Imre Vida
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717318302

Internet

http://www.sciencedirect.com/science/article/pii/S2211124717318302

Similar Items