Astragaloside IV Improves High-Fat Diet–Induced Hepatic Steatosis in Nonalcoholic Fatty Liver Disease Rats by Regulating Inflammatory Factors Level via TLR4/NF-κB Signaling Pathway

Astragaloside IV Improves High-Fat Diet–Induced Hepatic Steatosis in Nonalcoholic Fatty Liver Disease Rats by Regulating Inflammatory Factors Level via TLR4/NF-κB Signaling Pathway

Objective: Astragaloside IV (AS-IV) is the primary bioactive component purified from Astragalus membranaceus which is one of the traditional Chinese medicines. Research studies found that AS-IV has significant pharmacological effects on focal cerebral ischemia/reperfusion, cardiovascular disease, pu...

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Bibliographic Details
Main Authors: Ying-Li Liu, Qiu-Zan Zhang, Yan-Rong Wang, Li-Na Fu, Jing-Shu Han, Jing Zhang, Bang-Mao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
astragaloside IV
non-alcoholic fatty liver disease
toll like receptor 4
nuclear factor-kappa B
myeloid differentiation factor 88
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.605064/full

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https://www.frontiersin.org/articles/10.3389/fphar.2020.605064/full

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