Evaluation of a bone filler scaffold for local antibiotic delivery to prevent Staphylococcus aureus infection in a contaminated bone defect

Evaluation of a bone filler scaffold for local antibiotic delivery to prevent Staphylococcus aureus infection in a contaminated bone defect

Abstract We previously reported the development of an osteogenic bone filler scaffold consisting of degradable polyurethane, hydroxyapatite, and decellularized bovine bone particles. The current study was aimed at evaluating the use of this scaffold as a means of local antibiotic delivery to prevent...

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Bibliographic Details
Main Authors: Karen E. Beenken, Mara J. Campbell, Aura M. Ramirez, Karrar Alghazali, Christopher M. Walker, Bailey Jackson, Christopher Griffin, William King, Shawn E. Bourdo, Rebecca Rifkin, Silke Hecht, Daniel G. Meeker, David E. Anderson, Alexandru S. Biris, Mark S. Smeltzer
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89830-z

Internet

https://doi.org/10.1038/s41598-021-89830-z

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