Computational immunology meets bioinformatics: the use of prediction tools for molecular binding in the simulation of the immune system.

We present a new approach to the study of the immune system that combines techniques of systems biology with information provided by data-driven prediction methods. To this end, we have extended an agent-based simulator of the immune response, C-ImmSim, such that it represents pathogens, as well as...

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Bibliographic Details
Main Authors: Nicolas Rapin, Ole Lund, Massimo Bernaschi, Filippo Castiglione
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2855701?pdf=render