Bacille Calmette-Guérin Vaccine Strain Modulates the Ontogeny of Both Mycobacterial-Specific and Heterologous T Cell Immunity to Vaccination in Infants

Bacille Calmette-Guérin Vaccine Strain Modulates the Ontogeny of Both Mycobacterial-Specific and Heterologous T Cell Immunity to Vaccination in Infants

Differences in Bacille Calmette-Guérin (BCG) immunogenicity and efficacy have been reported, but various strains of BCG are administered worldwide. Since BCG immunization may also provide protection against off-target antigens, we sought to identify the impact of different BCG strains on the ontogen...

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Bibliographic Details
Main Authors: Agano Kiravu, Sophia Osawe, Anna-Ursula Happel, Trishana Nundalall, Jerome Wendoh, Sophie Beer, Nobomi Dontsa, Olatogni Berenice Alinde, Sikiratu Mohammed, Pam Datong, D. William Cameron, Kenneth Rosenthal, Alash'le Abimiku, Heather B. Jaspan, Clive M. Gray
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
BCG
vaccine strain
T cells
immunogenicity
Pertussis vaccine
Tetanus vaccine
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02307/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02307/full

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