In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways

Background: Polyphyllin VII (PP7), a steroidal saponin from Paris polyphylla, has been found to exert strong anticancer activity. Little is known about the anti-inflammatory property of PP7. In this study, the anti-inflammatory activity and its underlying mechanisms of PP7 were evaluated in lipopoly...

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Bibliographic Details
Main Authors: Chao Zhang, Chaoying Li, Xuejing Jia, Kai Wang, Yanbei Tu, Rongchun Wang, Kechun Liu, Tao Lu, Chengwei He
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/24/5/875