The short-term effects of ORKAMBI (lumacaftor/ivacaftor) on regional and distal lung structures using functional respiratory imaging

The short-term effects of ORKAMBI (lumacaftor/ivacaftor) on regional and distal lung structures using functional respiratory imaging

Background: Lumacaftor/ivacaftor (LUM/IVA) has shown modest benefits in previous research, but the exact effects in the cystic fibrosis (CF) lung remain unclear. This study aims to offer novel information on the mode of action of the cystic fibrosis transmembrane conductance regulator (CFTR)-modulat...

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Bibliographic Details
Main Authors: Eline Lauwers, Dennis Belmans, Benjamin Mignot, Kris Ides, Kim Van Hoorenbeeck, Annemiek Snoeckx, Cedric Van Holsbeke, Vicky Nowé, Eva Van Braeckel, Wilfried De Backer, Jan De Backer, Stijn Verhulst
Format: Article
Language:English
Published: SAGE Publishing 2021-09-01
Series:Therapeutic Advances in Respiratory Disease
Online Access:https://doi.org/10.1177/17534666211046774

Internet

https://doi.org/10.1177/17534666211046774

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