Fascin 2b is a component of stereocilia that lengthens actin-based protrusions.

Stereocilia are actin-filled protrusions that permit mechanotransduction in the internal ear. To identify proteins that organize the cytoskeleton of stereocilia, we scrutinized the hair-cell transcriptome of zebrafish. One promising candidate encodes fascin 2b, a filamentous actin-bundling protein f...

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Bibliographic Details
Main Authors: Shih-Wei Chou, Philsang Hwang, Gustavo Gomez, Carol A Fernando, Megan C West, Lana M Pollock, Jennifer Lin-Jones, Beth Burnside, Brian M McDermott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3082522?pdf=render