Conversion of 7α,12α-dihydroxycholest-4-en-3-one to 5α-cholestane-3α,7α,12α-triol by iguana liver microsomes

The role of 7α,l2α-dihydroxycholest-4-en-3-one as an intermediate in the formation of 5α-bile acids from cholesterol was investigated with liver preparations of Iguana iguana in vitro. The microsomal fraction of iguana liver catalyzed the transformation of 7α,12α-dihydroxycholest-4-en-3-one to 5α-ch...

Full description

Bibliographic Details
Main Authors: T. Hoshita, S. Shefer, E.H. Mosbach
Format: Article
Language:English
Published: Elsevier 1968-03-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520431244