Base-Promoted Annulation of Amidoximes with Alkynes: Simple Access to 2,4-Disubstituted Imidazoles

Base-Promoted Annulation of Amidoximes with Alkynes: Simple Access to 2,4-Disubstituted Imidazoles

An efficient construction of imidazole ring by a Cs<sub>2</sub>CO<sub>3</sub>-promoted annulation of amidoximes with terminal alkynes in DMSO has been developed. This protocol provides a simple synthetic route with high atom-utilization for the synthesis of 2,4-disubstituted...

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Bibliographic Details
Main Authors: Hina Mehmood, Muhammad Asif Iqbal, Le Lu, Ruimao Hua
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Molecules
Subjects:
base-promoted
annulation
amidoximes
alkynes
2,4-disubstituted imidazoles
Online Access:https://www.mdpi.com/1420-3049/25/16/3621

Internet

https://www.mdpi.com/1420-3049/25/16/3621

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