Looking into the Black Box: Insights into the Mechanisms of Somatic Cell Reprogramming

The dramatic discovery that somatic cells could be reprogrammed to induced pluripotent stem cells (iPSCs), by the expression of just four factors, has opened new opportunities for regenerative medicine and novel ways of modeling human diseases. Extensive research over the short time since the first...

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Bibliographic Details
Main Authors: Jeffrey L. Wrana, Azadeh Golipour, Laurent David, Payman Samavarchi-Tehrani
Format: Article
Language:English
Published: MDPI AG 2011-01-01
Series:Genes
Subjects:
iPS
BMP
Wnt
p53
MET
PKA
Online Access:http://www.mdpi.com/2073-4425/2/1/81/