MEIS-mediated suppression of human prostate cancer growth and metastasis through HOXB13-dependent regulation of proteoglycans

The molecular roles of HOX transcriptional activity in human prostate epithelial cells remain unclear, impeding the implementation of new treatment strategies for cancer prevention and therapy. MEIS proteins are transcription factors that bind and direct HOX protein activity. MEIS proteins are putat...

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Bibliographic Details
Main Authors: Calvin VanOpstall, Srikanth Perike, Hannah Brechka, Marc Gillard, Sophia Lamperis, Baizhen Zhu, Ryan Brown, Raj Bhanvadia, Donald J Vander Griend
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/53600