Efficient Mining of Variants From Trios for Ventricular Septal Defect Association Study

Efficient Mining of Variants From Trios for Ventricular Septal Defect Association Study

Ventricular septal defect (VSD) is a fatal congenital heart disease showing severe consequence in affected infants. Early diagnosis plays an important role, particularly through genetic variants. Existing panel-based approaches of variants mining suffer from shortage of large panels, costly sequenci...

Full description

Bibliographic Details
Main Authors: Peng Jiang, Yaofei Hu, Yiqi Wang, Jin Zhang, Qinghong Zhu, Lin Bai, Qiang Tong, Tao Li, Liang Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Genetics
Subjects:
trio-sequencing
k-mer filtering
variant calling
ventricular septal defect
association study
long non-coding RNA
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00670/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2019.00670/full

Similar Items