miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity.

miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity.

The interdependence of selective cues during development of regulatory T cells (Treg cells) in the thymus and their suppressive function remains incompletely understood. Here, we analyzed this interdependence by taking advantage of highly dynamic changes in expression of microRNA 181 family members...

Full description

Bibliographic Details
Main Authors: Marcin Łyszkiewicz, Samantha J Winter, Katrin Witzlau, Lisa Föhse, Rebecca Brownlie, Jacek Puchałka, Nikita A Verheyden, Heike Kunze-Schumacher, Esther Imelmann, Jonas Blume, Solaiman Raha, Takashi Sekiya, Akihiko Yoshimura, Jochen T Frueh, Evelyn Ullrich, Jochen Huehn, Siegfried Weiss, Maximiliano G Gutierrez, Immo Prinz, Rose Zamoyska, Natalia Ziętara, Andreas Krueger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-03-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.2006716

Internet

https://doi.org/10.1371/journal.pbio.2006716

Similar Items