In vivo competition and horizontal gene transfer among distinct Staphylococcus aureus lineages as major drivers for adaptational changes during long-term persistence in humans

In vivo competition and horizontal gene transfer among distinct Staphylococcus aureus lineages as major drivers for adaptational changes during long-term persistence in humans

Abstract Background The airways of the majority of adolescent cystic fibrosis (CF) patients are persistently colonized or infected by Staphylococcus aureus. Using whole genome sequencing, we studied the evolutionary traits within a S. aureus population in the airways of a CF patient hypothesizing th...

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Bibliographic Details
Main Authors: Lars Langhanki, Petya Berger, Janina Treffon, Francesco Catania, Barbara C. Kahl, Alexander Mellmann
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Microbiology
Subjects:
Staphylococcus aureus
Cystic fibrosis
Adaptation
Horizontal gene transfer
Genome sequencing
Online Access:http://link.springer.com/article/10.1186/s12866-018-1308-3

Internet

http://link.springer.com/article/10.1186/s12866-018-1308-3

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