Ellagic acid protects against diabetic nephropathy in rats by regulating the transcription and activity of Nrf2

Ellagic acid protects against diabetic nephropathy in rats by regulating the transcription and activity of Nrf2

This study examined if the protective effect of Ellagic acid (EA) against streptozotocin (STZ)-induced diabetic nephropathy (DN) in rats involves activation of Nrf2. Diabetes mellitus was induced by a single i.p dose of STZ (65 mg/kg). The Rats were divided into 5 groups (n = 12/each) and treated fo...

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Bibliographic Details
Main Authors: Jozaa Z. ALTamimi, Nora A. AlFaris, Ghedeir M. Alshammari, Reham I. Alagal, Dalal H. Aljabryn, Hussain Aldera, Bahauddeen M. Alrfaei, Mahmoud A. Alkhateeb, Mohammed A. Yahya
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Journal of Functional Foods
Subjects:
Ellagic acid
Diabetes
Nephropathy
Nrf2
Oxidative stress
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464621000463

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http://www.sciencedirect.com/science/article/pii/S1756464621000463

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