m6A mRNA Methylation Regulates Epithelial Innate Antimicrobial Defense Against Cryptosporidial Infection

m6A mRNA Methylation Regulates Epithelial Innate Antimicrobial Defense Against Cryptosporidial Infection

Increasing evidence supports that N6-methyladenosine (m6A) mRNA modification may play an important role in regulating immune responses. Intestinal epithelial cells orchestrate gastrointestinal mucosal innate defense to microbial infection, but underlying mechanisms are still not fully understood. In...

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Bibliographic Details
Main Authors: Zijie Xia, Jihao Xu, Eugene Lu, Wei He, Silu Deng, Ai-Yu Gong, Juliane Strass-Soukup, Gislaine A. Martins, Guoqing Lu, Xian-Ming Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
m6A
Cryptosporidium
intestinal epithelium
defense
ALKBH5
RNA stability
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.705232/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.705232/full

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