Cell Shape Regulation Based on Hepatocyte Sheet Engineering Technologies

The de novo engineering of a uniform hepatocyte sheet in vitro is considered as a novel approach for liver-directed therapeutics. Hepatocytes can be cultured on a temperature-responsive culture dishes coated with poly( N -isopropylacrylamide) (PIPAAm). Following multiple days of culturing, the hepat...

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Bibliographic Details
Main Authors: Soichi Takagi, Maki Ohno, Kazuo Ohashi M.D., Ph.D., Rie Utoh, Kohei Tatsumi, Teruo Okano
Format: Article
Language:English
Published: SAGE Publishing 2012-03-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368911X605312