Modeling the quantitative nature of neurodevelopmental disorders using Collaborative Cross mice

Modeling the quantitative nature of neurodevelopmental disorders using Collaborative Cross mice

Abstract Background Animal models for neurodevelopmental disorders (NDD) generally rely on a single genetic mutation on a fixed genetic background. Recent human genetic studies however indicate that a clinical diagnosis with Autism Spectrum Disorder (ASD) is almost always associated with multiple ge...

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Bibliographic Details
Main Authors: Remco T. Molenhuis, Hilgo Bruining, Myrna J. V. Brandt, Petra E. van Soldt, Hanifa J. Abu-Toamih Atamni, J. Peter H. Burbach, Fuad A. Iraqi, Richard F. Mott, Martien J. H. Kas
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Molecular Autism
Subjects:
Neurodevelopmental disorders
Autism
Animal models
Quantitative genetics
Genetic reference population
Behavioral neuroscience
Online Access:http://link.springer.com/article/10.1186/s13229-018-0252-2

Internet

http://link.springer.com/article/10.1186/s13229-018-0252-2

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