Single cell RNA-sequencing identifies a metabolic aspect of apoptosis in Rbf mutant

The function of the Retinoblastoma (Rb) protein is regulated by its cellular environment. Here, the authors perform single cell RNA-sequencing during Drosophila eye development and identify the impact of an Rbf mutation, which sensitises specific cells to apoptosis by changing metabolism.

Bibliographic Details
Main Authors: Majd M. Ariss, Abul B. M. M. K. Islam, Meg Critcher, Maria Paula Zappia, Maxim V. Frolov
Format: Article
Language:English
Published: Nature Publishing Group 2018-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07540-z