Antiviral antibody responses to systemic administration of an oncolytic RNA virus: the impact of standard concomitant anticancer chemotherapies

Antiviral antibody responses to systemic administration of an oncolytic RNA virus: the impact of standard concomitant anticancer chemotherapies

Background Oncolytic reovirus therapy for cancer induces a typical antiviral response to this RNA virus, including neutralizing antibodies. Concomitant treatment with cytotoxic chemotherapies has been hypothesized to improve the therapeutic potential of the virus. Chemotherapy side effects can inclu...

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Bibliographic Details
Main Authors: Kevin Harrington, Hardev Pandha, Alan Melcher, David Mansfield, Johann De Bono, Victoria Roulstone, Christine White, James Spicer, Richard Vile, Sophia N Karagiannis, Robert J Harris, Katie Twigger
Format: Article
Language:English
Published: BMJ Publishing Group 2021-07-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/7/e002673.full

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https://jitc.bmj.com/content/9/7/e002673.full

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