Human regulatory T cells of G-CSF mobilized allogeneic stem cell donors qualify for clinical application.

Recent clinical studies demonstrate the high potency of regulatory T cells (Tregs) to control graft-versus-host disease in hematopoietic stem cell transplantation (SCT). However, the adoptive transfer of Tregs is limited by their low frequency in unstimulated donors and considerable concerns that G-...

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Bibliographic Details
Main Authors: Sya N Ukena, Sarvari Velaga, Lilia Goudeva, Philipp Ivanyi, Sven Olek, Christine S Falk, Arnold Ganser, Anke Franzke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3520921?pdf=render