Inhibition of DNA Methylation Impairs Synaptic Plasticity during an Early Time Window in Rats

Although the importance of DNA methylation-dependent gene expression to neuronal plasticity is well established, the dynamics of methylation and demethylation during the induction and expression of synaptic plasticity have not been explored. Here, we combined electrophysiological, pharmacological, m...

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Bibliographic Details
Main Authors: Pablo Muñoz, Carolina Estay, Paula Díaz, Claudio Elgueta, Álvaro O. Ardiles, Pablo A. Lizana
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2016/4783836