Osmotin Protects H9c2 Cells from Simulated Ischemia-Reperfusion Injury through AdipoR1/PI3K/AKT Signaling Pathway

Osmotin Protects H9c2 Cells from Simulated Ischemia-Reperfusion Injury through AdipoR1/PI3K/AKT Signaling Pathway

Objective: This study aimed to investigate the effect of osmotin on myocardial ischemia/reperfusion (I/R), as well as the underlying mechanisms.Methods:In vitro I/R injury model was established on rat cardiac myoblast H9c2 cells by oxygen and glucose deprivation followed by reperfusion (OGD/R). Cell...

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Bibliographic Details
Main Authors: Jianhua Liu, Hua Sui, Jianlin Zhao, Yan Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Physiology
Subjects:
osmotin
acute myocardial infarction
ischemia-reperfusion injury
AdipoR1/PI3K signaling pathway
AKT signaling pathway
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.00611/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2017.00611/full

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