CSF SerpinA1 in Creutzfeldt–Jakob disease and frontotemporal lobar degeneration
Abstract Objective SerpinA1 (alpha‐1 antitrypsin) is an acute inflammatory protein, which seems to play a role in neurodegeneration and neuroinflammation. In Alzheimer’s disease and synucleinopathies, SerpinA1 is overexpressed in the brain and the cerebrospinal fluid (CSF) showing abnormal patterns...
Main Authors: | Samir Abu‐Rumeileh, Steffen Halbgebauer, Petra Steinacker, Sarah Anderl‐Straub, Barbara Polischi, Albert C. Ludolph, Sabina Capellari, Piero Parchi, Markus Otto |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-02-01
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Series: | Annals of Clinical and Translational Neurology |
Online Access: | https://doi.org/10.1002/acn3.50980 |
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