A Review on MS-Based Blood Biomarkers for Alzheimer’s Disease

by Patrick Oeckl, Markus Otto
Published 2019-12-01

Advantages and disadvantages of the use of the CSF Amyloid β (Aβ) 42/40 ratio in the diagnosis of Alzheimer’s Disease

by Oskar Hansson, Sylvain Lehmann, Markus Otto, Henrik Zetterberg, Piotr Lewczuk
Published 2019-04-01

Activity Regulation by Heteromerization of Arabidopsis Allene Oxide Cyclase Family Members

by Markus Otto, Christin Naumann, Wolfgang Brandt, Claus Wasternack, Bettina Hause
Published 2016-01-01

Neurofilament Light Chain as Biomarker for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

by Federico Verde, Federico Verde, Markus Otto, Vincenzo Silani, Vincenzo Silani
Published 2021-06-01

Stress cardiomyopathy associated with the first manifestation of multiple sclerosis: a case report

by Daniel Rapp, Mirjam Keßler, Elmar Pinkhardt, Markus Otto, Hayrettin Tumani, Makbule Senel
Published 2020-06-01

Cerebrospinal fluid immunoglobulin kappa light chain in clinically isolated syndrome and multiple sclerosis.

by Makbule Senel, Hayrettin Tumani, Florian Lauda, Stefan Presslauer, Rehaneh Mojib-Yezdani, Markus Otto, Johannes Brettschneider
Published 2014-01-01

Brain-Specific Cytoskeletal Damage Markers in Cerebrospinal Fluid: Is There a Common Pattern between Amyotrophic Lateral Sclerosis and Primary Progressive Multiple Sclerosis?

by Ahmed Abdelhak, Andreas Junker, Johannes Brettschneider, Jan Kassubek, Albert C. Ludolph, Markus Otto, Hayrettin Tumani
Published 2015-07-01

Glycoprotein NMB: a novel Alzheimer’s disease associated marker expressed in a subset of activated microglia

by Melanie Hüttenrauch, Isabella Ogorek, Hans Klafki, Markus Otto, Christine Stadelmann, Sascha Weggen, Jens Wiltfang, Oliver Wirths
Published 2018-10-01

Combined Analysis of CSF Tau, Aβ42, Aβ1–42% and Aβ1–40ox% in Alzheimer's Disease, Dementia with Lewy Bodies and Parkinson's Disease Dementia

by Mirko Bibl, Hermann Esselmann, Piotr Lewczuk, Claudia Trenkwalder, Markus Otto, Johannes Kornhuber, Jens Wiltfang, Brit Mollenhauer
Published 2010-01-01

Development and Validation of an Ultrasensitive Procalcitonin Sandwich Immunoassay

by Viviana A. Carcamo Yañez, Jens C. Göpfert, Markus Otto, Hayrettin Tumani, Andreas Peter, Thomas O. Joos
Published 2017-11-01

Soluble beta-amyloid precursor protein is related to disease progression in amyotrophic lateral sclerosis.

by Petra Steinacker, Lubin Fang, Jens Kuhle, Axel Petzold, Hayrettin Tumani, Albert C Ludolph, Markus Otto, Johannes Brettschneider
Published 2011-01-01

Longitudinal Serum Neurofilament Levels of Multiple Sclerosis Patients Before and After Treatment with First-Line Immunomodulatory Therapies

by André Huss, Makbule Senel, Ahmed Abdelhak, Benjamin Mayer, Jan Kassubek, Albert C. Ludolph, Markus Otto, Hayrettin Tumani
Published 2020-08-01

A Score Based on NfL and Glial Markers May Differentiate Between Relapsing–Remitting and Progressive MS Course

by André Huss, Markus Otto, Makbule Senel, Albert C. Ludolph, Ahmed Abdelhak, Ahmed Abdelhak, Hayrettin Tumani, Hayrettin Tumani
Published 2020-07-01

Tick-Borne Encephalitis: A Differential Pattern of Intrathecal Humoral Immune Response and Inflammatory Cell Composition Compared with Other Viral CNS Infections

by Makbule Senel, Daniel Rapp, Benjamin Mayer, Sarah Jesse, Sigurd D. Süssmuth, Markus Otto, Jan Lewerenz, Hayrettin Tumani
Published 2020-09-01

CSF Ubiquitin Levels Are Higher in Alzheimer’s Disease than in Frontotemporal Dementia and Reflect the Molecular Subtype in Prion Disease

by Samir Abu-Rumeileh, Patrick Oeckl, Simone Baiardi, Steffen Halbgebauer, Petra Steinacker, Sabina Capellari, Markus Otto, Piero Parchi
Published 2020-03-01

IgG antibodies against measles, rubella, and varicella zoster virus predict conversion to multiple sclerosis in clinically isolated syndrome.

by Johannes Brettschneider, Hayrettin Tumani, Ulrike Kiechle, Rainer Muche, Gayle Richards, Vera Lehmensiek, Albert C Ludolph, Markus Otto
Published 2009-11-01

CSF concentrations of cAMP and cGMP are lower in patients with Creutzfeldt-Jakob disease but not Parkinson's disease and amyotrophic lateral sclerosis.

by Patrick Oeckl, Petra Steinacker, Stefan Lehnert, Sarah Jesse, Hans A Kretzschmar, Albert C Ludolph, Markus Otto, Boris Ferger
Published 2012-01-01

A proteomic approach for the diagnosis of bacterial meningitis.

by Sarah Jesse, Petra Steinacker, Stefan Lehnert, Martin Sdzuj, Lukas Cepek, Hayrettin Tumani, Olaf Jahn, Holger Schmidt, Markus Otto
Published 2010-01-01

CSF Free Light Chains as a Marker of Intrathecal Immunoglobulin Synthesis in Multiple Sclerosis: A Blood-CSF Barrier Related Evaluation in a Large Cohort

by Makbule Senel, Fatemeh Mojib-Yezdani, Ulrike Braisch, Franziska Bachhuber, Jan Lewerenz, Albert C. Ludolph, Markus Otto, Hayrettin Tumani, Hayrettin Tumani
Published 2019-03-01

Cerebrospinal Fluid Biomarkers in Relation to MRZ Reaction Status in Primary Progressive Multiple Sclerosis

by Tilman Robinson, Ahmed Abdelhak, Tanima Bose, Edgar Meinl, Markus Otto, Uwe K. Zettl, Rick Dersch, Hayrettin Tumani, Sebastian Rauer, André Huss
Published 2020-11-01