Neuron Loss in Alzheimer’s Disease: Translation in Transgenic Mouse Models

by Oliver Wirths, Silvia Zampar
Published 2020-10-01

Characterization of a Mouse Model of Alzheimer’s Disease Expressing Aβ4-42 and Human Mutant Tau

by Silvia Zampar, Oliver Wirths
Published 2021-05-01

Loss of Hippocampal Calretinin and Parvalbumin Interneurons in the 5XFAD Mouse Model of Alzheimer’s Disease

by Naomi K. Giesers, Oliver Wirths
Published 2020-05-01

Neuron Loss in Transgenic Mouse Models of Alzheimer's Disease

by Oliver Wirths, Thomas A. Bayer
Published 2010-01-01

Effects of long-term environmental enrichment on anxiety, memory, hippocampal plasticity and overall brain gene expression in C57BL6 mice

by Melanie Hüttenrauch, Gabriela Salinas, Oliver Wirths
Published 2016-08-01

Physical Activity Ameliorates Impaired Hippocampal Neurogenesis in the Tg4-42 Mouse Model of Alzheimer’s Disease

by Anna-Lina Gerberding, Silvia Zampar, Martina Stazi, David Liebetanz, Oliver Wirths
Published 2019-12-01

Glycoprotein NMB: a novel Alzheimer’s disease associated marker expressed in a subset of activated microglia

by Melanie Hüttenrauch, Isabella Ogorek, Hans Klafki, Markus Otto, Christine Stadelmann, Sascha Weggen, Jens Wiltfang, Oliver Wirths
Published 2018-10-01

Evaluation of cerebrospinal fluid glycoprotein NMB (GPNMB) as a potential biomarker for Alzheimer’s disease

by Freyja Aichholzer, Hans-Wolfgang Klafki, Isabella Ogorek, Jonathan Vogelgsang, Jens Wiltfang, Norbert Scherbaum, Sascha Weggen, Oliver Wirths
Published 2021-05-01

A two-step immunoassay for the simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer’s d...

by Hedieh Shahpasand-Kroner, Hans-W. Klafki, Chris Bauer, Johannes Schuchhardt, Melanie Hüttenrauch, Martina Stazi, Caroline Bouter, Oliver Wirths, Jonathan Vogelgsang, Jens Wiltfang
Published 2018-12-01

N-truncated Aβ4–x peptides in sporadic Alzheimer’s disease cases and transgenic Alzheimer mouse models

by Oliver Wirths, Susanne Walter, Inga Kraus, Hans W. Klafki, Martina Stazi, Timo J. Oberstein, Jorge Ghiso, Jens Wiltfang, Thomas A. Bayer, Sascha Weggen
Published 2017-10-01

Synergistic Effect on Neurodegeneration by N-Truncated Aβ4−42 and Pyroglutamate Aβ3−42 in a Mouse Model of Alzheimer's Disease

by Jose S. Lopez-Noguerola, Nicolai M. E. Giessen, Maximilian Ueberück, Julius N. Meißner, Charlotte E. Pelgrim, Johnathan Adams, Oliver Wirths, Yvonne Bouter, Thomas A. Bayer
Published 2018-03-01

Development and Technical Validation of an Immunoassay for the Detection of APP_669–711 (Aβ_−3–40) in Biological Samples

by Hans W. Klafki, Petra Rieper, Anja Matzen, Silvia Zampar, Oliver Wirths, Jonathan Vogelgsang, Dirk Osterloh, Lara Rohdenburg, Timo J. Oberstein, Olaf Jahn, Isaak Beyer, Ingolf Lachmann, Hans-Joachim Knölker, Jens Wiltfang
Published 2020-09-01

The presubiculum is preserved from neurodegenerative changes in Alzheimer’s disease

by Christina E. Murray, Priya Gami-Patel, Eleni Gkanatsiou, Gunnar Brinkmalm, Erik Portelius, Oliver Wirths, Wendy Heywood, Kaj Blennow, Jorge Ghiso, Janice L. Holton, Kevin Mills, Henrik Zetterberg, Tamas Revesz, Tammaryn Lashley
Published 2018-07-01

No alterations of hippocampal neuronal number and synaptic bouton number in a transgenic mouse model expressing the β-cleaved C-terminal APP fragment

by Bart P.F Rutten, Oliver Wirths, Wilma D.J Van de Berg, Stefan F Lichtenthaler, Jochen Vehoff, Harry W.M Steinbusch, Hubert Korr, Konrad Beyreuther, Gerd Multhaup, Thomas A Bayer, Christoph Schmitz
Published 2003-03-01