N-Truncated Aβ Starting at Position Four—Biochemical Features, Preclinical Models, and Potential as Drug Target in Alzheimer’s Disease

by Thomas A. Bayer
Published 2021-08-01

Intracellular accumulation of amyloid-beta - a predictor for synaptic dysfunction and neuron loss in Alzheimer's disease

by Thomas A Bayer
Published 2010-03-01

Neuron Loss in Transgenic Mouse Models of Alzheimer's Disease

by Oliver Wirths, Thomas A. Bayer
Published 2010-01-01

Synaptic Alterations in Mouse Models for Alzheimer Disease—A Special Focus on N-Truncated Abeta 4-42

by Katharina Dietrich, Yvonne Bouter, Michael Müller, Thomas A. Bayer
Published 2018-03-01

Disturbed Copper Bioavailability in Alzheimer's Disease

by Daniela Kaden, Ashley I. Bush, Ruth Danzeisen, Thomas A. Bayer, Gerd Multhaup
Published 2011-01-01

miRNA Alterations Elicit Pathways Involved in Memory Decline and Synaptic Function in the Hippocampus of Aged Tg4-42 Mice

by Yvonne Bouter, Tim Kacprowski, Fanny Rößler, Lars R. Jensen, Andreas W. Kuss, Thomas A. Bayer
Published 2020-09-01

In vivo Imaging With 18F-FDG- and 18F-Florbetaben-PET/MRI Detects Pathological Changes in the Brain of the Commonly Used 5XFAD Mouse Model of Alzheimer's Disease

by Timon N. Franke, Caroline Irwin, Thomas A. Bayer, Winfried Brenner, Nicola Beindorff, Caroline Bouter, Yvonne Bouter
Published 2020-09-01

Impaired Cu/Zn-SOD activity contributes to increased oxidative damage in APP transgenic mice

by Katrin Schuessel, Stephanie Schäfer, Thomas A. Bayer, Christian Czech, Laurent Pradier, Franz Müller-Spahn, Walter E. Müller, Anne Eckert
Published 2005-02-01

Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain

by Dieter Lütjohann, Andreas Brzezinka, Esther Barth, Dorothee Abramowski, Matthias Staufenbiel, Klaus von Bergmann, Konrad Beyreuther, Gerd Multhaup, Thomas A. Bayer
Published 2002-07-01

18F-FDG-PET Detects Drastic Changes in Brain Metabolism in the Tg4–42 Model of Alzheimer’s Disease

by Caroline Bouter, Philipp Henniges, Timon N. Franke, Caroline Irwin, Carsten Oliver Sahlmann, Marius E. Sichler, Nicola Beindorff, Thomas A. Bayer, Yvonne Bouter
Published 2019-01-01

N-truncated Aβ4–x peptides in sporadic Alzheimer’s disease cases and transgenic Alzheimer mouse models

by Oliver Wirths, Susanne Walter, Inga Kraus, Hans W. Klafki, Martina Stazi, Timo J. Oberstein, Jorge Ghiso, Jens Wiltfang, Thomas A. Bayer, Sascha Weggen
Published 2017-10-01

Synergistic Effect on Neurodegeneration by N-Truncated Aβ4−42 and Pyroglutamate Aβ3−42 in a Mouse Model of Alzheimer's Disease

by Jose S. Lopez-Noguerola, Nicolai M. E. Giessen, Maximilian Ueberück, Julius N. Meißner, Charlotte E. Pelgrim, Johnathan Adams, Oliver Wirths, Yvonne Bouter, Thomas A. Bayer
Published 2018-03-01

Analysis of Motor Function in the Tg4-42 Mouse Model of Alzheimer’s Disease

by Jannek M. Wagner, Marius E. Sichler, Eva M. Schleicher, Timon N. Franke, Caroline Irwin, Maximilian Johannes Löw, Nicola Beindorff, Caroline Bouter, Thomas A. Bayer, Yvonne Bouter
Published 2019-05-01

Diesel engine exhaust accelerates plaque formation in a mouse model of Alzheimer’s disease

by Maja Hullmann, Catrin Albrecht, Damiën van Berlo, Miriam E. Gerlofs-Nijland, Tina Wahle, Agnes W. Boots, Jean Krutmann, Flemming R. Cassee, Thomas A. Bayer, Roel P. F. Schins
Published 2017-08-01

Frontotemporal dysregulation of the SNARE protein interactome is associated with faster cognitive decline in old age

by Alfredo Ramos-Miguel, Andrea A. Jones, Ken Sawada, Alasdair M. Barr, Thomas A. Bayer, Peter Falkai, Sue E. Leurgans, Julie A. Schneider, David A. Bennett, William G. Honer
Published 2018-06-01

Amyloid precursor protein (APP) mediated regulation of ganglioside homeostasis linking Alzheimer's disease pathology with ganglioside metabolism.

by Marcus O W Grimm, Eva G Zinser, Sven Grösgen, Benjamin Hundsdörfer, Tatjana L Rothhaar, Verena K Burg, Lars Kaestner, Thomas A Bayer, Peter Lipp, Ulrike Müller, Heike S Grimm, Tobias Hartmann
Published 2012-01-01

No alterations of hippocampal neuronal number and synaptic bouton number in a transgenic mouse model expressing the β-cleaved C-terminal APP fragment

by Bart P.F Rutten, Oliver Wirths, Wilma D.J Van de Berg, Stefan F Lichtenthaler, Jochen Vehoff, Harry W.M Steinbusch, Hubert Korr, Konrad Beyreuther, Gerd Multhaup, Thomas A Bayer, Christoph Schmitz
Published 2003-03-01

Deciphering the molecular profile of plaques, memory decline and neuron-loss in two mouse models for Alzheimer’s disease by deep sequencing

by Yvonne eBouter, Tim eKacprowski, Tim eKacprowski, Robert eWeissmann, Katharina eDietrich, Henning eBorgers, Andreas eBrauß, Christian eSperling, Oliver eWirths, Mario eAlbrecht, Mario eAlbrecht, Lars R. Jensen, Andreas W. Kuss, Thomas A Bayer
Published 2014-04-01