Transcriptional signature associated with early rheumatoid arthritis and healthy individuals at high risk to develop the disease.

Transcriptional signature associated with early rheumatoid arthritis and healthy individuals at high risk to develop the disease.

Little is known regarding the mechanisms underlying the loss of tolerance in the early and preclinical stages of autoimmune diseases. The aim of this work was to identify the transcriptional profile and signaling pathways associated to non-treated early rheumatoid arthritis (RA) and subjects at high...

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Bibliographic Details
Main Authors: N Macías-Segura, J E Castañeda-Delgado, Y Bastian, D Santiago-Algarra, J D Castillo-Ortiz, A L Alemán-Navarro, E Jaime-Sánchez, M Gomez-Moreno, C A Saucedo-Toral, Edgar E Lara-Ramírez, M Zapata-Zuñiga, L Enciso-Moreno, R González-Amaro, C Ramos-Remus, J A Enciso-Moreno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5870959?pdf=render

Internet

http://europepmc.org/articles/PMC5870959?pdf=render

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