Wen-Dan Decoction Improves Negative Emotions in Sleep-Deprived Rats by Regulating Orexin-A and Leptin Expression

Wen-Dan Decoction Improves Negative Emotions in Sleep-Deprived Rats by Regulating Orexin-A and Leptin Expression

Wen-Dan Decoction (WDD), a formula of traditional Chinese medicine, has been clinically used for treating insomnia for approximately 800 years. However, the therapeutic mechanisms of WDD remain unclear. Orexin-A plays a key role in the sleep-wake cycle, while leptin function is opposite to orexin-A....

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Bibliographic Details
Main Authors: Fengzhi Wu, Yuehan Song, Feng Li, Xin He, Jie Ma, Ting Feng, Binghe Guan, Liye Wang, Sinai Li, Xiaolan Liu, Yan Liu, Meng Mao, Jing Liu, Shijing Bai, Cai Song
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2014/872547

Internet

http://dx.doi.org/10.1155/2014/872547

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