The Induction of Circulating, ACAID-Inducing Monocytes Requires CCR2/CCL2-Dependent Migration of Circulating F4/80 Cells into the Anterior Chamber

To determine the origin of peripheral blood mononuclear cells (PBMC) that activate regulatory T cells in anterior chamber-associated immune deviation (ACAID), fluorescein-labeled PBMC were intravenously injected into mice before the mice received an intracameral injection of antigen. Six-24 hr after...

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Bibliographic Details
Main Authors: Robert E Cone, Subhasis Chattopadhyay, Roshan Pais, Sourojit Bhowmick, Roshanak Sharafieh, Yen Lemire, James O'rourke
Format: Article
Language:English
Published: SAGE Publishing 2010-01-01
Series:Ophthalmology and Eye Diseases
Online Access:https://doi.org/10.4137/OED.S6113